Research on Resveratrol's mechanism of immunity in anti-aging

Zhong Yao Cai. 2006 May;29(5):464-7
Yao Y, Tian T, Nan KJ.
Internal Medicine of Oncology, Medical College, Xi'an Jiaotong University, China.

OBJECTIVE: To research resveratrol's mechanism of immunity in anti-aging and explore the new clinical use of resveratrol.

METHODS: The sub acute ageing model was made by continuous subcutaneous injection of D galactose to mice inducing reactive oxygen species (ROS). Meanwhile, the resveratrol was given and its effect on anti-ageing was observed.

RESULTS: The resveratrol could increase the content of SOD and decrease the content of MDA in serum. There was no change in spleen index, but thymus index increased obvionsly. There was no change in the quantity of CD4+, but the quantity of CD8+ increased and the ratio of CD4+/CD8+ was decreased. The serum IL-6 and IL-8 level were decreased obviously.

CONCLUSION: The resveratrol possessed the function to anti-ageing and the applications foreground in anti-ageing.